Gertrude Elion wurde als Tochter des Zahnarztes Robert Elion und seiner Frau Bertha, geb. Gertrude Belle Elion (1918-1999) En 1988 Gertrude B. Elion recibía el premio nobel de fisiología y medicina junto con George H. Hitchings y Sir James Black por sus investigaciones sobre el tratamiento con determinados fármacos. ELION, GERTRUDE BELLE (b.New York, New York, 23 January 1918;. Gertrude Belle Elion (Nueva York, 23 de enero de 1918-Chapel Hill, Carolina del Norte, 21 de febrero de 1999) fue una bioquímica y farmacóloga estadounidense, que recibió en 1988 el Premio Nobel de Fisiología y Medicina por sus «descubrimientos de los principios clave sobre el desarrollo y el tratamiento de medicamentos». During this period, she also suffered the death of her fiancé and never married. Gertrude Belle Elion (* 23. d.Chapel Hill, North Carolina, 21 February 1999),pharmacology, antimetabolites, immunosuppressors, anticancer drugs, antiviral drugs. After several unfulfilling jobs she entered graduate school at New York University, receiving her M.S. Elion y su equipo destacaron también en el desarrollo de un agente químico, el acyclovir, muy beneficioso para el tratamiento de las infecciones causadas por los virus del herpes. White was the author of 'Charlotte's Web' and 'Stuart Little,' contributor to 'The New Yorker' and co-author of 'The Elements of Style. The manpower shortage of World War II proved a boon for Elion, as she found work as a quality control chemist at Quaker Maid Company, and then as a research chemist at Johnson & Johnson.
[1] En 1939, sus pequeños ahorros le permitieron entrar en la escuela de graduados de la Universidad de Nueva York, en la que no tenía ni una sola compañera, aunque ello no hacía que se sintiera extraña. Gertrude Belle Elion was born in New York City on January 23, 1918. Fue galardonada con el Premio Nobel de Fisiología y Medicina de 1988 por el desarrollo de medicamentos contra el cáncer y otras enfermedades, y que además fueron los precursores para la síntesis de otros nuevos.
This article was most recently revised and updated by Gertrude (“Trudy”) Belle Elion’s greatest legacy is the thousands of lives touched by the drugs she and her associates developed for the treatment of leukemia, gout, rejection of transplanted organs, and herpes, among other disorders. “Interaction of Anticancer Drugs with Enzymes.” In
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Rather than relying on trial-and-error methods, they used the differences in biochemistry between normal human cells and pathogens (disease-causing agents) to design drugs that would block viral infections. Gertrude (“Trudy”) Belle Elion’s greatest legacy is the thousands of lives touched by the drugs she and her associates developed for the treatment of leukemia, gout, rejection of transplanted organs, and herpes, among other disorders. She found part-time jobs as a lab assistant and went back to school at New York University. No por haber descubierto nuevas sustancias, sino por las ideas novedosas que utilizaron para llegar a ellos. "King of the Blues" B.B. in 1941. Elion and Hitchings set out on an unorthodox course of creating medicines by studying the chemical composition of diseased cells.
Elion worked as a substitute high school teacher for a few years while finishing work on her master's degree, which she earned in 1941. She won a Nobel Prize for Medicine in 1988. Gertrude Belle Elion (Nueva York, 1918 - Chapel Hill, 1999) Bioquímica y farmacóloga estadounidense. “The Synthesis of 6-Thioguanine,” with George H. Hitchings. Elion was the … Litauen.
Gertrude Elion died on Sunday, February 21, 1999, in Chapel Hill, North Carolina, where she lived. Learn more about Gertrude B. Elion, the female scientist who helped develop drugs to treat diseases such as malaria and AIDS, at Biography.com. Though she never married, she enjoyed being the "favorite aunt" to her brother's children.Gertrude Elion officially retired in 1983, but she remained active, holding the titles of scientist emeritus and consultant at her old company. At Burroughs Wellcome, Elion and her associates exploited the biochemical differences between normal cells and rapidly dividing, pathogenic cells such as cancer, bacteria, and viruses in order to develop new drugs. Elion and her team developed drugs to combat leukemia, herpes and AIDS. Elion never completed a Ph.D. She began the doctoral program at Brooklyn Polytechnic but was forced to leave after two years when the college dean made her choose between her education and her job. Sie entdeckte wichtige Prinzipien der Arzneimitteltherapie. She was a member of the National Academy of Sciences, the American Academy of Pharmaceutical Scientists, the American Chemical Society, and the American Association of Cancer Research, of which she was president in 1983–1984. In 1997, she was granted the Lemelson-MIT Lifetime Achievement Award.We strive for accuracy and fairness. They also discovered treatments to reduce the body's rejection of foreign tissue in kidney transplants between unrelated donors. She won a Nobel Prize for medicine in 1988.© 2020 Biography and the Biography logo are registered trademarks of A&E Television Networks, LLC. Con toda la información obtenida, estudiaron la forma de elaborar drogas y medicamentos que inhibieran el desarrollo de una patología y sobre todo de un cáncer.Una de las principales moléculas sintetizada por Gertrude Belle Elion fue resultado de su estudio sobre los ácidos nucleicos: la 2-amino-6-mercaptopurina, una base púrica que contiene azufre y que no se encuentra en los animales; esta sustancia interfiere con la introducción de otras purinas en la formación de la cadena de ácidos nucleicos, por lo que inhíbe el crecimiento de ciertos tipos de cánceres, especialmente el de sangre. Así, en 1944, obtuvo su Master en Química por dicha universidad.Gertrude B. Elion trabajó en los laboratorios de varias empresas, pero eran más bien trabajos de control de calidad y no tenían ninguna relación con la investigación; no obstante, aprendió mucho sobre el instrumental del laboratorio, hasta que, después de buscar en muchas agencias de trabajo, fue cautivada por un puesto como ayudante de Ambos, Hitchings y Elion, consiguieron obtener fármacos eficaces contra la leucemia, la gota, las infecciones urinarias, la malaria, el herpes viral y diversas enfermedades autoinmunes. Gertrude Belle Elion died on February 21, 1999 at the age of 81.